Two people died in the second of two crashes reported early this morning in the southbound lanes ofInterstate 65 near the 48-mile-marker, police report.

That wreck occurred in the backup of an earlier wreck involving two semitrailers, according to Sgt. Stephen Wheeles with the Indiana State Police.

More details about both wrecks will be released as they become available, police said.

Updated at 12:17 p.m.

Both southbound lanes of Interstate 65 at the 48-mile-marker have reopened after two early morning wrecks, police report.

Sgt. Stephen Wheeles said information about those wrecks, one involving two semitrailers, would be released when available.

Updated at 10:40 a.m.

Motorists will experience single lane closures on northbound Interstate 65 south of Columbus from Thursday evening to Friday morning while Indiana Department of Transportation maintenance and bridge personnel make asphalt and concrete repairs.

INDOT crews will be onsite at mile marker 65.5 patching areas of I-65’s left northbound lane. Once completed, the right northbound lane will close for repairs. One northbound lane on I-65 will remain open at all times.

Restrictions are scheduled to begin at 6 p.m. Thursday and be lifted by 6 a.m. Friday.

Inclement weather could postpone patching operations.